Permeability of Lipid Membranes to Hydrogen Peroxide
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چکیده
منابع مشابه
Ionic Permeability of Thin Lipid Membranes
Ultrathin (black) lipid membranes were made from sheep red cell lipids dissolved in n-decane. The presence of aliphatic alcohols in the aqueous solutions bathing these membranes produced reversible changes in the ionic permeability, but not the osomotic permeability. Heptanol (8 mM), for example, caused the membrane resistance (R(m)) to decrease from >10(8) to about 10(5) ohm-cm(2) and caused a...
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The osmotic permeability coefficient, P(f), and the tagged water permeability coefficient, P(d), were determined for thin (<100 A) lipid membranes formed from ox brain lipids plus DL-alpha-tocopherol; their value of approximately 1 x 10(-3) cm/sec is within the range reported for plasma membranes. It was established that P(f) = P(d). Other reports that P(f) > P(d) can be attributed to the prese...
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A sensitive fluorescence technique was used to measure transport of organic solutes through lipid bilayer membranes and to relate permeability to the functional groups of the solute, lipid composition of the membrane, and pH of the medium. Indole derivatives having ethanol, acetate, or ethylamine in the 3-position, representing neutral, acidic, and basic solutes, respectively, were the primary ...
متن کاملThe Permeability of Thin Lipid Membranes to Bromide and Bromine
Thin lipid (optically black) membranes were made from sheep red cell lipids dissolved in n-decane. The flux of Br across these membranes was measured by the use of tracer (82)Br. The unidirectional flux of Br (in 50-100 mM NaBr) was 1-3 x 10(-12) mole/cm(2)sec. This flux is more than 1000 times the flux predicted from the membrane electrical resistance (>10(8) ohm-cm(2)) and the transference nu...
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Impairment of endothelial barrier function is implicated in many vascular and inflammatory disorders. One prevalent mechanism of endothelial dysfunction is an increase in reactive oxygen species under oxidative stress. Previous reports have demonstrated that hydrogen peroxide (H(2)O(2)), a highly stable reactive oxygen species that modulates physiological signaling pathways, also enhances endot...
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ژورنال
عنوان ژورنال: Free Radical Biology and Medicine
سال: 2020
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2020.10.082